Status:
UNKNOWN
Multicenter Observational Study on Practice of Ventilation in Brain Injured Patients
Lead Sponsor:
University of Milano Bicocca
Conditions:
Mechanical Ventilation
Acute Brain Injury
Eligibility:
All Genders
18+ years
Brief Summary
Rationale Several experimental and clinical studies have shown how brain injury can cause secondary lung injury. Lung injury could be due either to mechanical ventilation- often necessary in brain inj...
Detailed Description
INTRODUCTION AND RATIONALE Mechanical ventilation (MV) is a frequently applied and often a life-saving strategy in neurocritically ill patients. Paradoxically, ventilation itself has the potential to ...
Eligibility Criteria
Inclusion
- Adult patients admitted to the ICU with a diagnosis of
- traumatic brain injury or
- cerebrovascular diseases (intracranial hemorrhage, subarachnoid hemorrhage, ischemic stroke)
- Patients requiring intubation and mechanical ventilation in the ICU
- Expected ventilation for more than 48 hours
Exclusion
- Age \< 18 years
- Pregnant patients
- Patients not intubated or not mechanically ventilated or receiving only non-invasive ventilation (i.e., the patient never received invasive ventilation during the present admission)
- Patients under invasive mechanical ventilation before the 7-day period of inclusion
- Expected ventilation or death\< 48 hours
Key Trial Info
Start Date :
August 23 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT04459884
Start Date
August 23 2021
End Date
December 1 2023
Last Update
May 26 2023
Active Locations (1)
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1
ASST-Monza
Monza, MB, Italy, 20900