Status:

UNKNOWN

Injection of Ranibizumab Versus Combination of Ranibizumab and Triamcinolone Acetate for (CRVO)

Lead Sponsor:

Assiut University

Conditions:

Ophthalmopathy

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

PHASE3

Brief Summary

To compare the clinical effectiveness of ranibizumab and combination of ranibizumab and triamcinolone for the treatment of macular oedema secondary to CRVO

Eligibility Criteria

Inclusion

  • Patients 18 years of age or older with visual impairment resulting from macular edema secondary to CRVO.
  • A BCVA approximate Snellen equivalents, 20/40.

Exclusion

  • Use of intra-vitreal anti-VEGF injections 3 months or less before baseline.
  • Pan-retinal laser photocoagulation 3 months or less before baseline,
  • Topical ocular or systemic corticosteroids administered for 30 consecutive days.
  • Intraocular or periocular corticosteroid use 3 months or less before screening (study eye),
  • Use of intraocular corticosteroid implants,
  • Uncontrolled glaucoma (intraocular pressure \[IOP\] 30 mmHg with medication) at the time of screening or baseline,
  • iris neovascularization or neo-vascular glaucoma.

Key Trial Info

Start Date :

May 16 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04460001

Start Date

May 16 2019

End Date

December 1 2021

Last Update

July 7 2020

Active Locations (1)

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1

Wael

Asyut, Egypt, 11711