Status:
ACTIVE_NOT_RECRUITING
Exercise-Induced Metabolic Compensation; a Physiological Adaptive Response to Exercise Training
Lead Sponsor:
Tel Aviv University
Collaborating Sponsors:
University of Colorado, Denver
Conditions:
Exercise Training
Eligibility:
All Genders
21-45 years
Phase:
NA
Brief Summary
The primary aim of this proposal is to identify changes in the volume of highly metabolic organs (liver, kidneys, and brain) that occur as a physiological adaptation to exercise training and lower the...
Detailed Description
Using a clinical trial type protocol, 16 overweight (body mass index: 25-30 kg/m2) men (n=8) and women (n=8) aged 21 to 45 years will exercise for 3 months in a moderate intensity regimen of 20 kcal/w...
Eligibility Criteria
Inclusion
- Overweight \[body mass index (BMI) 25-30
Exclusion
- Participation in another exercise or weight loss program in the last 6 months
- Non-stable weight (\>±5%) over the past 6 months
- Current regular exercise \> 1 hour per week
- Smoking within the past 6 months
- Being post-menopausal, breastfeeding, pregnancy, or having been pregnant within the past 6 months
- Previous bariatric surgery
- Cardiopulmonary disease (e.g., recent myocardial infarction or unstable angina)
- Musculoskeletal or neuromuscular impairments that preclude exercise training
- Having other health issues include cancer, diabetes, thyroid disease, hypertension, chronic renal failure, cognitive impairments
- Use of drugs that potentially impact body metabolism.
Key Trial Info
Start Date :
March 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2024
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04460040
Start Date
March 27 2021
End Date
November 1 2024
Last Update
February 22 2024
Active Locations (1)
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1
Tel Aviv University
Tel Aviv, Other, Israel, 6997801