Status:

UNKNOWN

The Predictive Value of Alarm Symptoms in Patients With Function Constipation Based on Roman IV

Lead Sponsor:

Second Affiliated Hospital of Xi'an Jiaotong University

Conditions:

Function Constipation

Eligibility:

All Genders

18-75 years

Brief Summary

Functional constipation is one of the five most common gastrointestinal diseases in outpatient visits. It is known that the global prevalence of chronic constipation is estimated to be 14%, and the pr...

Eligibility Criteria

Inclusion

  • Patients with constipation that meet the diagnostic criteria for functional constipation in Rome III or IV (specific conditions are as follows) (1) Must include two or more of the following:
  • More than 25% of bowel movements feel laborious;
  • Over 25% of the bowel movements are dry ball dung or hard dung; (Bristol Manure Character Scale Type 1-2)
  • More than 25% of bowel movements have an inexhaustible feeling;
  • More than 25% of bowel movements require manual assistance;
  • More than 25% of bowel movements need to be assisted by manual techniques (such as assisting bowel movements with fingers and basin support);
  • Less than 3 times per week (spontaneous defecation). (2) Dirty feces rarely occur when laxatives are not used. (3) Does not meet the diagnostic criteria for irritable bowel syndrome. (Symptoms appear at least 6 months before diagnosis, and meet the above (existence) diagnostic criteria within the past 3 months)
  • Age ≥18 years old;
  • From 2020.07 to 2020.12, visit the outpatient clinic of our hospital and perform colonoscopy;
  • Blood routine, fecal routine and fecal occult blood examination within 6 months.

Exclusion

  • Inflammatory bowel disease, celiac disease and other organic intestinal diseases, history of metabolic diseases (abnormal thyroid function and diabetes, etc.);
  • Severe neurological, mental and psychological diseases, or those with severe organ dysfunction;
  • Abdominal surgery;
  • Patients during pregnancy, possible pregnancy and lactation;
  • Those who have a history of colonoscopy within the past 6 months, and those who have evaluated intestinal status;
  • Refuse to participate in this study.

Key Trial Info

Start Date :

July 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2020

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT04460404

Start Date

July 1 2020

End Date

December 31 2020

Last Update

July 7 2020

Active Locations (1)

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1

The second affiliated hospital of xi'an jiaotong university

Xi'an, Shaanxi, China, 710004