Status:
TERMINATED
Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk
Lead Sponsor:
University Hospital, Montpellier
Collaborating Sponsors:
Clinea psychiatrie France
Conditions:
Major Depressive Disorder
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
Joiner's interpersonal theory of suicide postulates that the wish of death comes from feelings of perceived burdensomeness and thwarted belongingness. But, only people who have acquired the capability...
Detailed Description
Aim: The first objective of this project is to test different pain mechanisms that could be involved in the increase of pain thresholds and tolerance in suicidal patients. The second objective is to t...
Eligibility Criteria
Inclusion
- Inclusion Criteria for all patients:
- Woman;
- Being aged between 18 and 65 years;
- Currently meeting the DSM-5 major depressive episode criteria;
- Being able to understand the nature, purpose and methodology of the study and agreeing to cooperate during the assessments;
- Having signed informed consent;
- Being affiliated with a social security or equivalent.
- Inclusion Criteria specific to each group:
- Recent attempters: women having recently attempted suicide (less than 72 hours)
- Past attempters: women having a past suicide attempt (more than 72 hours)
- Affective control: women without lifetime history of suicidal behaviour (affective control group).
- Exclusion Criteria for all patients:
- Existence of current psychotic or mixed characteristics;
- Lifetime history of schizoaffective disorder or schizophrenia;
- Current substance dependence (within the last 6 months);
- Existence of mental retardation or serious medical comorbidity interfering with measures (HIV, diabetes, cancer, chronic inflammatory pathology, neurological disorder);
- Having taken painkillers within the last 24 hours preceding the evaluation;
- Existence of a usual or current treatment with analgesics or NSAIDs (daily analgesic treatment more than 3 months);
- Existence of a sensory or cognitive handicap;
- Pregnant or lactating woman.
Exclusion
Key Trial Info
Start Date :
November 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 21 2024
Estimated Enrollment :
144 Patients enrolled
Trial Details
Trial ID
NCT04461327
Start Date
November 25 2020
End Date
February 21 2024
Last Update
March 25 2025
Active Locations (2)
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1
University Hospital of Montpellier
Montpellier, Occitanie, France, 34295
2
Clinic La Lironde
Saint-Gély-du-Fesc, Occitanie, France, 34981