Status:

ACTIVE_NOT_RECRUITING

Tomosynthesis as Primary Test for Breast Cancer Screening

Lead Sponsor:

Azienda USL Reggio Emilia - IRCCS

Collaborating Sponsors:

AULSS 9 Scaligera di Verona

IRCCS Policlinico S. Donato, Milano

Conditions:

Breast Cancer

Eligibility:

FEMALE

45-65 years

Phase:

NA

Brief Summary

Randomized trial comparing tomosynthesis plus synthetic 2D Mammography vs Digital Mammography in respect to incidence of advanced cancers (interval and following round) and interval cancers.

Detailed Description

This is a companion study of the other Italian studies on tomosyntesis as primary screening test for breast cancer: RETomo (NCT02698202), PROTEUS (NCT02590315), IMPETO (NCT03587259). The investigators...

Eligibility Criteria

Inclusion

  • Women scheduled for a new round of mammographic screening
  • resident in the province

Exclusion

  • previous breast cancer diagnosis
  • pregnancy or suspicion of pregnancy
  • presence of BRCA1/2 gene mutation
  • Previous Digital Breast Tomosynthesis performed
  • unable to understand informed consent
  • chemotherapy in progress
  • presence of breast implant

Key Trial Info

Start Date :

July 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2029

Estimated Enrollment :

10156 Patients enrolled

Trial Details

Trial ID

NCT04461808

Start Date

July 15 2019

End Date

April 30 2029

Last Update

June 25 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia

Reggio Emilia, Italy, Italy, 42122

2

IRCCS Policlinico San Donato

Milan, Italy

3

Azienda Ospedaliera Universitaria Integrata

Verona, Italy

4

Azienda Ulss 9 Scaligera

Verona, Italy