Status:

COMPLETED

A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy

Lead Sponsor:

Janssen-Cilag S.p.A.

Conditions:

Depressive Disorder, Major

Suicidal Ideation

Eligibility:

All Genders

18-74 years

Brief Summary

The purpose of the study is to describe the pharmacological and non-pharmacological treatment utilization pathways in Italian routine clinical practice of participants with Major Depressive Disorder (...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Participant must meet Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5) diagnostic criteria for single episode or recurrent Major Depressive Disorder (MDD), based upon clinical assessment
  • In the physician's opinion the current depressive episode is moderate-to-severe in terms of severity.
  • In the physician's opinion, acute psychiatric hospitalization is clinically warranted due to participant's current active suicidal ideation with intent
  • Participant must be capable of discernment
  • Participant must be able to read and write in the Italian language
  • Participant must have signed the informed consent form (ICF) indicating that he/she understands the study purpose and is willing to participate in the study
  • Participant is in the site's catchment area, as evaluated by the Investigator
  • Exclusion criteria:
  • Participant currently (that is, at the time of enrolment and based upon clinical assessment) meets DSM-5 criteria for psychotic disorder, bipolar or related disorders, antisocial personality disorder, borderline personality disorder, intellectual disability, autism spectrum disorder, dementia
  • Participant meets the DSM-5 severity criteria for moderate or severe substance or alcohol use disorder (except for nicotine or caffeine) within the 6 months before enrolment, based upon clinical assessment
  • Participant has participated in or is currently enrolled in any clinical trial with experimental treatments within the current major depressive episode

Exclusion

    Key Trial Info

    Start Date :

    June 23 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    November 8 2021

    Estimated Enrollment :

    136 Patients enrolled

    Trial Details

    Trial ID

    NCT04463108

    Start Date

    June 23 2020

    End Date

    November 8 2021

    Last Update

    April 27 2025

    Active Locations (24)

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    Page 1 of 6 (24 locations)

    1

    ASST Spedali Civili Brescia

    Brescia, Italy, 25123

    2

    Ospedale Santissima Trinità

    Cagliari, Italy, 00000

    3

    Ospedale Sant'Antonio Abate

    Cantù, Italy, 22063

    4

    Ospedale Vittorio Emanuele

    Catania, Italy, 95124