Status:

COMPLETED

Endothelial Dysfunction in Reversible Cerebral Vasoconstriction Syndrome

Lead Sponsor:

Nantes University Hospital

Conditions:

Reversible Cerebral Vasoconstriction Syndrome

Eligibility:

All Genders

18-80 years

Brief Summary

Reversible Cerebral Vasoconstriction Syndrome (RCVS) is a syndrome described at the end of the 20th century. Generally, it has a benign course. It is revealed by acute headaches, in different circumst...

Detailed Description

The investigators lead a case control study to find a systemic endothelial dysfunction by the using of Complior device. Complior is a mechanographer who calculates pulse wave velocity (PWV). Pulse wav...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients :
  • Aged from 18 to 80 years old
  • RVCS diagnosis evoked on clinic and radiologic finding
  • Last headache was 15 days ago
  • Oral consent
  • Register in French social security
  • Inclusion criteria for control :
  • Aged from 18 to 80 years old
  • Hypothesis of RCVS in clinical presentation and on cerebral imaging
  • Last headache less than 3 days old
  • Oral consent
  • Register in French social security
  • Person under guardianship, curatorship or safeguarding of justice
  • Exclusion Criteria:
  • Non inclusion criteria for patient :
  • Pregnant women
  • Tobacco, coffee, alcohol, drugs or vasoactive recreational substances use within 2 hours prior to the examination.
  • Person under guardianship, curatorship or safeguarding of justice
  • Non sinusal rhythm on EKG
  • Impossible of Breath holding for 30 secondes
  • Exclusion criteria for patient :
  • \- No reversibility at 3 months
  • Non inclusion criteria for control :
  • Pregnant women
  • Tobacco, coffee, alcohol, drugs or vasoactive recreational substances use within 2 hours prior to the examination.
  • Non sinusal rhythm on EKG
  • Impossible of Breath holding for 30 secondes

Exclusion

    Key Trial Info

    Start Date :

    January 29 2021

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 12 2024

    Estimated Enrollment :

    62 Patients enrolled

    Trial Details

    Trial ID

    NCT04463212

    Start Date

    January 29 2021

    End Date

    January 12 2024

    Last Update

    January 24 2024

    Active Locations (1)

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    1

    Nantes University Hospital

    Nantes, Loire-Atlantique, France, 44093