Status:

COMPLETED

The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology

Lead Sponsor:

Stanford University

Conditions:

Hypotension

Fontan Physiology

Eligibility:

All Genders

Phase:

EARLY_PHASE1

Brief Summary

The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures. Because patients who have underg...

Detailed Description

Patients with Fontan physiology are at increased risk of developing hypotension during periods of illness or with anesthesia. These patients have changes in venous capacitance, compliance, and venomot...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • 1\. All patients scheduled for cardiac catheterization at Lucile Packard Children's Hospital with Fontan circulation
  • Exclusion criteria:
  • Critical illness severe enough to preclude extended cardiac catheterization time
  • Patients already on vasopressin
  • Patients with pulmonary hypertension.
  • Patient not scheduled for cardiac catheterization at Lucile Packard Children's Hospital (LPCH).

Exclusion

    Key Trial Info

    Start Date :

    August 12 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    February 15 2022

    Estimated Enrollment :

    28 Patients enrolled

    Trial Details

    Trial ID

    NCT04463394

    Start Date

    August 12 2020

    End Date

    February 15 2022

    Last Update

    May 14 2025

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Stanford University Medical Center

    Stanford, California, United States, 94305

    2

    Stanford University

    Stanford, California, United States, 94305