Status:

COMPLETED

Effects of COVID-19 Infection on Beta-cell Function in Euglycemic Patients

Lead Sponsor:

University of Milan

Collaborating Sponsors:

Luigi Sacco University Hospital

Conditions:

COVID19

BETA-CELL FUNCTION

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

In recent months, a new coronavirus, SARS-CoV-2, has been identified as the cause of a serious lung infection named COVID-19 by the World Health Organization. This virus has spread rapidly among the n...

Detailed Description

The project is monocentric, interventional, non-pharmacological, non-profit. Patients will be enrolled in hospital for confirmed COVID-19 infection (with reverse transcriptase-polymerase chain reactio...

Eligibility Criteria

Inclusion

  • Inclusion criteria for COVID-19 positive patients
  • Male and female patients with COVID19 and normal basal blood sugar, unprecedented in diabetes or impaired fasting glucose or impaired glucose tolerance
  • Age\> 18 years and \<80 years
  • Availability to informed consent and corporate privacy
  • Inclusion criteria for healthy subjects
  • Male and female patients not affected by COVID19, unprecedented in diabetes or impaired fasting glucose or impaired glucose tolerance
  • Age\> 18 years and \<80 years
  • Availability to informed consent and corporate privacy
  • Exclusion criteria for COVID-19 positive patients
  • Age \<18 years
  • Previous history of diabetes or impaired fasting glucose or impaired glucose tolerance
  • Severe liver failure
  • Severe kidney failure
  • Exclusion criteria for healthy subjects
  • Age \<18 years
  • Previous history of diabetes or impaired fasting glucose or impaired glucose tolerance
  • Positivity to the nasopharyngeal swab for SARS-CoV-2
  • Severe liver failure
  • Severe kidney failure
  • Inclusion criteria for T2D patients
  • Male and female patients not affected by COVID19 with a diagnosis of type 2 diabetes
  • Age\> 18 years and \<80 years
  • Availability to informed consent and corporate privacy
  • Exclusion criteria for T2D patients
  • Age \<18 years
  • Positivity to the nasopharyngeal swab for SARS-CoV-2
  • Severe liver failure
  • Severe kidney failure

Exclusion

    Key Trial Info

    Start Date :

    June 30 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 31 2021

    Estimated Enrollment :

    90 Patients enrolled

    Trial Details

    Trial ID

    NCT04463849

    Start Date

    June 30 2020

    End Date

    December 31 2021

    Last Update

    May 10 2023

    Active Locations (1)

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    1

    Sacco University Hospital

    Milan, MI, Italy, 20157