Status:

UNKNOWN

Double Dose Magnesium Sulphate in Moderate-severe Asthma in Paediatrics

Lead Sponsor:

Oman Medical Speciality Board

Conditions:

Asthma in Children

Eligibility:

All Genders

3-13 years

Phase:

PHASE2

PHASE3

Brief Summary

Introduction : . In Oman the prevalence of asthma was estimated to be 7.3% of adults and 12.7% of children . Magnesium sulphate is the second line treatment, many studies had shown that it has benefic...

Detailed Description

Research questions : In children 3 to 13 years of age presenting to the pediatric emergency room with moderate to severe asthma exacerbation, does double dose Magnesium sulfate improve asthma severit...

Eligibility Criteria

Inclusion

  • Physican diagnosed of asthma
  • Age 3-13 years
  • Children presenting with acute moderate- severe asthma (PRAM score ≥ 5)
  • Failed to respond to initial treatment of acute asthma
  • Not known to have allergy from MgSO4

Exclusion

  • Mild exacerbation of asthma (initial PRAM score ≤4)
  • Other comorbid present : Significant heart disease , arrhythmias , chronic kidney disease , cystic fibrosis , operated trachea-esophageal fistula , known or operated for vascular ring , trisomy 21

Key Trial Info

Start Date :

August 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04465175

Start Date

August 1 2020

End Date

December 1 2021

Last Update

July 13 2020

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