Status:
RECRUITING
Coronavirus Disease 2019 (COVID-19) During Pregnancy: Prevalence of Seroconversion, Effect on Maternal and Perinatal Outcomes and Risk of Vertical Transmission (COVID-MAP)
Lead Sponsor:
Chinese University of Hong Kong
Collaborating Sponsors:
Peking University First Hospital
Hospital Universitario de Torrejón
Conditions:
COVID-19
Eligibility:
FEMALE
18+ years
Brief Summary
The objectives of this proposal are to: 1) determine the rate of SARS-CoV-2 seroconversion in unselected pregnant women in Hong Kong; 2) determine the rate of SARS-CoV-2 infection in women presenting ...
Detailed Description
With over 10 million individuals infected worldwide, the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health cris...
Eligibility Criteria
Inclusion
- Objective 1: Seroconversion during pregnancy
- Inclusion criteria:
- Pregnant women who attended for Down syndrome screening (DSS) at 11-13 weeks
- Had serum sample taken between 1 November 2019 and 1 June 2020 consented for stored serum for future research
- Intended to deliver at the booking hospital.
- Objective 2: SARS-CoV-2 and pregnancy loss
- Inclusion criteria:
- •Pregnant women presenting with first and second trimester miscarriage in Hong Kong and Spain, as well as those with stillbirth during periods of 6 and 12 months, respectively.
- Objective 3: Pregnancy course and perinatal outcome
- Inclusion criteria:
- •Pregnant women affected by COVID-19
- Objective 4: Vertical transmission
- Inclusion criteria:
- •Pregnant women affected by COVID-19
- Objective 5: Potential mechanisms for vertical transmission
- Inclusion criteria:
- •Pregnant women affected by COVID-19
Exclusion
Key Trial Info
Start Date :
May 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT04465474
Start Date
May 1 2020
End Date
December 31 2024
Last Update
February 8 2024
Active Locations (10)
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1
Peking University First Hospital
Beijing, Beijing Municipality, China
2
Kwong Wah Hospital
Hong Kong, Hong Kong
3
Pamela Youde Nethersole Eastern Hospital
Hong Kong, Hong Kong
4
Princess Margaret Hospital
Hong Kong, Hong Kong