Status:
COMPLETED
The Impact of a Smartphone-based Personalized Intervention on Cognitive and Cerebrovascular Health in CIRCLE-CHINA
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborating Sponsors:
Shaoxing Gaobu Street Community Health Service Center
Shaoxing Mashan Street Community Health Service Center
Conditions:
Cognitive Impairment
Stroke
Eligibility:
All Genders
45-74 years
Phase:
NA
Brief Summary
This smartphone-based personalized multiple intervention study aims to prevent cognitive impairment and reduce dementia and cerebrovascular events in 45-74 year old persons with high risk of stroke in...
Detailed Description
Patients with ≥ 3 stroke risk factors (including hypertension, dyslipidemia, diabetes, atrial fibrillation or valvular heart disease, smoking history, obvious overweight or obesity, lack of exercise, ...
Eligibility Criteria
Inclusion
- aged 45-74 years
- high risk of stroke (with ≥ 3 of 8 stroke risk factors, including hypertension, dyslipidemia, diabetes, atrial fibrillation or valvular heart disease, smoking history, obvious overweight or obesity, lack of exercise, family history of stroke, or with transient ischemic attack)
Exclusion
- previously diagnosed dementia
- previously diagnosed stroke (both cerebral infarction and hemorrhage)
- suspected dementia after clinical assessment by study physician at screening visit
- disorders affecting safe engagement in the intervention (eg, malignant disease, major depression, symptomatic cardiovascular disease, revascularisation within 1 year previously)
- severe loss of vision, hearing, or communicative ability;
- disorders preventing cooperation as judged by the study physician
- coincident participation in another intervention trial
- any MRI contraindications
Key Trial Info
Start Date :
July 21 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2025
Estimated Enrollment :
238 Patients enrolled
Trial Details
Trial ID
NCT04465812
Start Date
July 21 2020
End Date
May 31 2025
Last Update
June 15 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Second Affilated Hospital of Zhejiang University, School of Medicine
Hangzhou, Zhejiang, China, 310009