Status:
COMPLETED
Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection
Lead Sponsor:
Cambridge University Hospitals NHS Foundation Trust
Collaborating Sponsors:
Imperial College Healthcare NHS Trust
Royal Cornwall Hospitals Trust
Conditions:
Olfactory Disorder
COVID19
Eligibility:
All Genders
18-85 years
Brief Summary
This study is designed to investigate the acuity of olfactory dysfunction in COVID-19 positive patients in the United Kingdom. In particular defining severity with objective testing and determining if...
Detailed Description
The main objective of this study is to evaluate olfactory acuity by means of a multidimensional assessment protocol to objectively demonstrate the severity of olfactory dysfunction in patients diagnos...
Eligibility Criteria
Inclusion
- Patients who are presenting to hospital with symptoms of SARS CoV-2 infection.
- Patients who go on to develop a positive SARS CoV-2 test.
- Patients who can give a valid written informed consent.
- Patients who are motivated to participate in the study.
- Adult patients aged 18 years - 85 years.
Exclusion
- Patients who cannot give a valid written informed consent.
- Patients who are not willing or not motivated to participate in the study.
- Patients with negative SARS CoV-2 tests.
- Patients with nasal pathologies like severe deviated nasal septum, nasal masses, head trauma or previously known chronic rhinosinusitis with polyps or on medication for more than 6 months/year for at least one year for chronic rhinosinusitis.
- Patients with any diagnosed neurological disease known to affect olfactory function will be excluded from the study.
- Patients unable to read in the English language.
Key Trial Info
Start Date :
July 2 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 30 2023
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT04466982
Start Date
July 2 2020
End Date
March 30 2023
Last Update
June 29 2025
Active Locations (3)
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1
Addenbrookes Hospital
Cambridge, United Kingdom, CB2 0QQ
2
Charing Cross Hospital
London, United Kingdom, W6 8RF
3
Royal Cornwall Hospital
Truro, United Kingdom, TR1 3LQ