Status:
COMPLETED
Investigation of Inflammacheck to Measure Exhaled Breath Condensate Hydrogen Peroxide in Respiratory Conditions
Lead Sponsor:
Portsmouth Hospitals NHS Trust
Conditions:
Respiratory Disease
Eligibility:
All Genders
16+ years
Brief Summary
People with lung conditions can suffer significantly with their symptoms and often require multiple trips to their GP or secondary care before a diagnosis is made. It can be difficult to diagnose lung...
Detailed Description
Lung disease is one of the largest contributors to morbidity and mortality in the UK, with 20% of the population diagnosed with, or receiving treatment for a respiratory condition. Methods of diagnos...
Eligibility Criteria
Inclusion
- Male or Female, aged ≥16 years
- A confirmed, clinician made diagnosis of the following (supported by standard accepted diagnostic criteria):
- Asthma with a ≤10 pack year smoking history (confirmed by spirometry and/or airway inflammation and function tests)
- COPD (confirmed by spirometry)
- Bronchiectasis (confirmed by CT scan)
- Interstitial Lung Disease (confirmed by CT scan and MDT/specialist consensus)
- has or is eventually proven to have a histological OR radiological and MDT confirmed diagnosis of primary lung cancer, and not yet started treatment for this
- current pneumonia (confirmed by chest imaging)
- Breathing Pattern Disorder, with no other significant respiratory co-morbidity (specialist confirmed)
- Healthy controls (defined as no current clinical diagnosis of, or be receiving treatment for, a lung or other significant medical disorder).
- Willing and able to give informed consent for participation in the study.
- In a stable state (at least 4 weeks after treatment of an exacerbation of their respiratory disease)
Exclusion
- Existing co-morbidities that may prevent them from performing spirometry, for those with asthma, COPD, or healthy controls, with no spirometry in the previous 12 months (at the discretion of the clinical investigator).
- Unable to comprehend the study, provide informed consent, and unable to perform any of the study procedures.
- Requirement of supplemental oxygen (pneumonia participants only)
Key Trial Info
Start Date :
September 13 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 13 2022
Estimated Enrollment :
425 Patients enrolled
Trial Details
Trial ID
NCT04467190
Start Date
September 13 2019
End Date
October 13 2022
Last Update
April 7 2023
Active Locations (1)
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1
Portsmouth Hospitals NHS Trust
Portsmouth, United Kingdom, PO6 3LY