Status:

COMPLETED

Tart Cherry Supplementation & Gut Microbiome and Inflammation

Lead Sponsor:

Ohio University

Conditions:

Inflammation

Glucose Regulation

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

There has been a rapid increase in researching the use of tart cherry supplements in the past 5 years, particularly for inflammatory conditions. Many formulations of cherry supplements exist, however ...

Detailed Description

Participants will consume a tart cherry or placebo product for 30 days and attend 5 visits in the Exercise Physiology Lab at Ohio University over the 30 day period. They will self-collect a stool samp...

Eligibility Criteria

Inclusion

  • 18-55 years old
  • participate in 150 minutes of exercise per week
  • non-smoker
  • have no known allergy to cherries or cherry juice
  • are not taking food supplements (turmeric/curcumin, cherry products, greens, etc.). -You must have access to the internet and be willing to record your food intake, physical activity and sleep quality/duration during the study.

Exclusion

  • not 18-55 years old.
  • have quit smoking less than one year ago.
  • have been diagnosed with a metabolic disorder such as diabetes, thyroid disorder, or high cholesterol.
  • are currently being treated for arthritis or an inflammatory condition, such as arthritis, gout, lupus or Sjogren's syndrome.
  • are currently being treated for cardiovascular disease, high blood pressure, fibromyalgia, or irritable bowel syndrome.
  • are pregnant.
  • regularly consume cherries or are allergic to cherries.
  • currently use anti-inflammatory medications.
  • have used corticosteroids in the last two months.
  • are not willing to follow a low polyphenol diet.
  • are not willing to have blood drawn on 4 occasions.
  • are not willing to provide a stool sample on 3 occasions.
  • do not have access to the internet.

Key Trial Info

Start Date :

March 18 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2021

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04467372

Start Date

March 18 2019

End Date

July 1 2021

Last Update

September 9 2021

Active Locations (1)

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Ohio University Exercise Physiology Lab

Athens, Ohio, United States, 45701