Status:
RECRUITING
Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery
Lead Sponsor:
Peking University Third Hospital
Conditions:
Degenerative Lumbar Spinal Stenosis
Degenerative Disc Disease
Eligibility:
All Genders
18-80 years
Brief Summary
This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for lumbar degenerative disease are prospectively enrolled and followed. Important adjacent pre-e...
Detailed Description
Adjacent segment pathologies (ASP), including radiological adjacent segment degeneration (ASDeg) and adjacent segment disease (ASDis) after lumbar fusion surgeries have been troubling complications. T...
Eligibility Criteria
Inclusion
- A clear diagnosis of lumbar spinal stenosis, and surgical level of L4- S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);
- Failed at least eight weeks conservative treatment;
Exclusion
- Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4;
- Preoperative sagittal and coronal imbalance of the spine;
- Lumbar infection and/or tumor diseases;
- A previous history of lumbar fusion surgery.
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2032
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT04467944
Start Date
January 1 2018
End Date
December 31 2032
Last Update
July 13 2020
Active Locations (1)
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1
Peking University Third Hospital
Beijing, Beijing Municipality, China, 100191