Status:

COMPLETED

Virtual Reality Treatment for Adults With Chronic Back Pain

Lead Sponsor:

CognifiSense Inc.

Collaborating Sponsors:

University of Colorado, Boulder

National Institute of Nursing Research (NINR)

Conditions:

Chronic Pain

Back Pain Lower Back Chronic

Eligibility:

All Genders

21-70 years

Phase:

NA

Brief Summary

Participants with chronic back pain will complete an online eligibility questionnaire. After signing a consent form, eligible participants enter a two-week baseline period ("Baseline Period") during w...

Eligibility Criteria

Inclusion

  • Participants aged 21 to 70 with Chronic Back Pain.
  • Chronic Back Pain will be defined according to criteria established by recent NIH task force. Pain duration must be ≥ 3 months, with back pain being an ongoing problem for at least half the days of last 6 months; i.e., either pain every day for past 3 months, or half or more of the days for past 6+ months.
  • Subjects must rate pain intensity at ≥ 4/10 on Brief Pain Inventory (average pain over the last week).
  • Participants must also be comfortable and able to communicate via email, text message, or phone in English. Participants must also be comfortable using a video-conferencing service such as Zoom to complete the on-line sessions.

Exclusion

  • Applicants, who are pregnant, planning pregnancy, or breastfeeding
  • Back pain associated with compensation / litigation within 1 year.
  • Leg pain greater than back pain (suggests neuropathic pain; may be less responsive to psychological therapy).
  • Chronic pain other than chronic back pain.
  • Diagnoses of schizophrenia, multiple personality dissociative identity disorder.
  • History of major depressive disorder not controlled with medication or other conditions that produce significant cognitive or emotional disability.
  • History of substance abuse.
  • Inability to undergo MRI (determined at screening; see XVI: Risks to Participants).
  • Any clinically significant unstable medical abnormality or acute or chronic disease of cardiovascular, gastrointestinal, respiratory (e.g., chronic obstructive pulmonary disease), hepatic, or renal systems; including: history of cardiovascular disease or issues (e.g., recent heart attack), stroke; brain surgery, or brain tumor; Diabetes; cancer (last 12 months); diagnosis of a specific inflammatory disorder: rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Lupus; polymyositis; or Cauda Equina syndrome.
  • History of seizure disorder, epilepsy, convulsions, or increased intracranial pressure anytime except pediatric febrile seizures.
  • History of vertigo, dizziness, susceptibility to motion sickness
  • History of head injury within 6 months,
  • Unexplained, unintended weight loss of 'â• 20 lbs in past year.
  • Self-reported history of (digital) eye strain or computer vision syndrome.
  • Unable or unwilling to meet study attendance requirements.
  • MRI contraindications as determined by MRI safety screen (e.g., pregnancy, metal in body, claustrophobia, using the standard screen conducted by the MRI imaging facility).

Key Trial Info

Start Date :

June 9 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 14 2021

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT04468074

Start Date

June 9 2020

End Date

June 14 2021

Last Update

June 23 2022

Active Locations (1)

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1

University of Colorado, Boulder

Boulder, Colorado, United States, 80301