Status:

COMPLETED

A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)

Lead Sponsor:

Bristol-Myers Squibb

Conditions:

Healthy Participants

Eligibility:

All Genders

21-65 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to assess levels in blood plasma of BMS-986278 and the food effect in healthy participants.

Eligibility Criteria

Inclusion

  • Healthy participants, as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs, and clinical laboratory determinations in the opinion of the investigator
  • Women and men must agree to follow specific methods of contraception

Exclusion

  • Women of childbearing potential (WOCBP) and Women who are pregnant or breastfeeding
  • Any significant acute or chronic medical condition that presents a potential risk to the participant and/or that may compromise the objectives of the study
  • Exposure to any investigational drug or placebo within 4 weeks of first study treatment administration.
  • History of any significant drug and/or food allergies (such as anaphylaxis or hepatotoxicity)
  • Other protocol-defined inclusion/exclusion criteria apply

Key Trial Info

Start Date :

July 10 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 7 2020

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT04468815

Start Date

July 10 2020

End Date

October 7 2020

Last Update

May 10 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

ICON (LPRA) - Salt Lake

Salt Lake City, Utah, United States, 84124

A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole) | DecenTrialz