Status:
TERMINATED
Influence of Luteolin on Memory in Healthy Subjects
Lead Sponsor:
University of Basel
Conditions:
Memory
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Proof of concept study on physiological processes (forgetting and memory functions, attention, working memory) in participants after multiple administration of the dietary supplement Luteolin.
Detailed Description
In the experimental phase the investigator will administer 500 mg Luteolin (2x250 mg capsules) per day formulated for oral administration for 7.5 days (first intake: visit 1/3 in the morning; last int...
Eligibility Criteria
Inclusion
- male or female
- healthy
- normotensive (BP between 90/60mmHg and 140/90mmHg)
- BMI \<30 kg/m2
- aged between 18 and 40 years
- native or fluent German-speaking
- able and willing to give written informed consent as documented by signature and comply with the requirements of the study protocol
Exclusion
- Bodyweight \<50 kg
- acute or chronic psychiatric disorder (e.g. major depression, psychoses, somatoform disorder, suicidal tendency)
- concomitant acute or chronic disease state (e.g. renal failure, hepatic dysfunction, cardiovascular disease, acute infections etc.)
- women who are pregnant or breast feeding
- intention to become pregnant during the course of the study
- known or suspected non-compliance, drug or alcohol abuse
- inability to follow the procedures of the study, e.g. due to language problems, psychological disorders
- participation in another study with investigational drug within the 30 days preceding and during the present study
- enrolment of the investigator, his/her family members, employees and other dependent persons
- participation in one of our previous studies using the same memory tests in the past 2 years
- Psychoactive drugs and alcoholic beverages 3 days (psychoactive drugs) resp. 12 hours (alcohol) before test visits 1-4.
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04468854
Start Date
January 1 2020
End Date
March 15 2020
Last Update
July 13 2020
Active Locations (1)
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1
University of Basel, Division of Cognitive Neuroscience
Basel, Canton of Basel-City, Switzerland, 4055