Status:
RECRUITING
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
Lead Sponsor:
University of Southern California
Collaborating Sponsors:
Dana-Farber Cancer Institute
Conditions:
Sedentary Behavior
Affect
Eligibility:
All Genders
8-11 years
Phase:
NA
Brief Summary
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs. single bouts of sustained exercise on metabolic, cognitive...
Detailed Description
Rationale: Sedentary behavior (SB) contributes to increased risk for obesity and metabolic disease, cognitive deficits, affect disorders, and cardiovascular disease over the lifespan. These are critic...
Eligibility Criteria
Inclusion
- Age 8-11 years-old
- Good general health
- BMI≥85th percentile
Exclusion
- Significant cardiac or pulmonary disease likely to or resulting in hypoxia or decreased perfusion
- Diagnosis of T2DM and/or presence of other endocrinologic disorders leading to obesity (e.g., Cushing Syndrome)
- Current or past anti-psychotic drug use that would affect metabolism
- Non-diet treatment for hypertension or dyslipidemia
- Precocious puberty and/or receiving androgen and estrogen therapy
- Medication use known to affect body composition/weight
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
188 Patients enrolled
Trial Details
Trial ID
NCT04469790
Start Date
March 1 2022
End Date
August 31 2026
Last Update
June 5 2025
Active Locations (1)
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1
Britni Ryan Belcher, PhD, MPH
Los Angeles, California, United States, 90032