Status:

COMPLETED

Elmo Respiratory Support Project - COVID-19

Lead Sponsor:

Escola de Saúde Pública do Ceará

Conditions:

COVID-19

Respiratory Failure With Hypoxia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The number of COVID-19 cases has been growing exponentially, so that the industrialized economies are facing a significant shortage in the number of ventilators available to meet the demands imposed b...

Detailed Description

Objectives: 1. Validate the functionalities to fulfill the requirements and evaluate the usability of the Elmo System and 2. Evaluate the effectiveness of the Elmo system in the treatment of support t...

Eligibility Criteria

Inclusion

  • Adult patient, age\> or = 18 years, both sexes;
  • Patient should be alert, oriented, and cooperative;
  • When using oxygen therapy by CNO2\> or = 4L/min, MR\> or = 8 L/min of O2 or MV 50%, for maintain SpO2\> 92%;
  • Gasometric parameters (pre ELMO, up to 30 min before): pH\> 7.35, PaO2\> 60 mmHg;
  • RX or chest CT scan with bilateral parenchymal opacities from the last 24 hours.

Exclusion

  • Exacerbation of Asthma, Chronic Obstructive Pulmonary Disease (COPD), pulmonary fibrosis or other lung diseases;
  • Hemodynamic instability (SBP \<90 mmHg or MBP \<65 mmHg or need for vasoactive drugs);
  • Pneumothorax or pneumomediastinum;
  • Respiratory acidosis (pH \<7.35 with PaCO2 \>46mmHg);
  • Signs of respiratory muscle fatigue (paradoxical breathing, accessory muscle use);
  • Nausea or vomiting;
  • Disorders of the auditory canal;
  • Use of nasoenteric or nasogastric feeding tubes;
  • Imminent risk of respiratory arrest.

Key Trial Info

Start Date :

June 25 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 30 2020

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04470258

Start Date

June 25 2020

End Date

November 30 2020

Last Update

April 20 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Leonardo Da Vinci

Fortaleza, Brazil