Status:
COMPLETED
Carotid Doppler and EEOT for Fluid Responsiveness Prediction
Lead Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions:
Septic Shock
Eligibility:
All Genders
Phase:
NA
Brief Summary
Fluid responsiveness prediction prior to fluid challenge administration is a topic of interest, which has been extensively investigated, but remains challenging. In clinical practice, functional hemo...
Detailed Description
The aim of the present study is to investigate whether changes in systolic peak velocity (ΔV peak-CA) and in flow time (ΔFT) using carotid artery Doppler during an End-Expiratory Occlusion Test (EEOT)...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- sedated and mechanically ventilated patients
- need a fluid challenge
- hypotension defined as a systolic arterial pressure ≤90 mmHg
- tachycardia ≥100 beats/min
- urinary flow ≤0.5 mL/kg/min for 2 hrs
- Exclusion criteria:
- age\< 18 y old
- significant valvular heart diseases
- cardiac arrhythmia
- peripheral arterial disease
- common carotid artery stenosis greater than 50%
- spontaneous breathing.
Exclusion
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04470856
Start Date
January 1 2019
End Date
December 31 2020
Last Update
July 1 2021
Active Locations (1)
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1
Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, RM, Italy, 00168