Status:
COMPLETED
Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC
Lead Sponsor:
National Hospital Organization Minami Kyoto Hospital
Conditions:
High-flow Nasal Cannula
Exercise Capacity
Eligibility:
All Genders
20-90 years
Phase:
NA
Brief Summary
The purpose of this study is to compare the exercise capacity (6-min walking distance) under the following 4 conditions using High-flow nasal cannula (HFNC); 1. FIO2 value that the minimum SpO2 value ...
Detailed Description
In the pervious study, the investigators demonstrated that 4 weeks of training using both high FIO2 and high flow through an HFNC significantly improved the 6MWD compared with training using a 6 L/min...
Eligibility Criteria
Inclusion
- Subjects with a minimum SPO2 of 88% or less during performing 6MWT under HFNC (FIO2 0.21 and a flow rate of 10L/min)
- Subjects who have been clinically stable for the last 2 weeks
- Subjects with written informed consent to participate in this study
Exclusion
- Subjects with severe cardiovascular disease, liver disease, neurological disease, and renal failure
- Subjects who needed antimicrobial agent or steroid administration for pneumonia and exacerbation of respiratory disease in the last 2 weeks
- Subjects who cannot undergo 6MWT due to severe heart failure, arteriosclerosis obliterans or spinal disease
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 29 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04471220
Start Date
July 1 2020
End Date
September 29 2022
Last Update
September 30 2022
Active Locations (1)
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1
National Hospital Organization Minami Kyoto Hospital
Jōyō, Kyoto, Japan, 610-0113