Status:
UNKNOWN
Longitudinal Follow-up Study in Two Chinese Hypertension Cohorts
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Conditions:
Hypertension
Eligibility:
All Genders
40-80 years
Brief Summary
Essential hypertension is a complex trait that results from interaction between environmental factors and genetic factors. Salt sensitivity is the genetic susceptibility of blood pressure to salt, and...
Detailed Description
This study is a longitudinal cohort follow-up study. The main contents include: (1) Questionnaire design: the questionnaire is designed according to the research contents and purposes. The standard q...
Eligibility Criteria
Inclusion
- Hanzhong cohort of Adolescent Hypertension Study:
- • adolescents aged 6-15 years old in over 20 schools of three towns (Qili, Laojun and Shayan) in Hanzhong, Shaanxi, China.
- Mei county cohort of adult salt-sensitive hypertension study:
- Han individuals in rural northern China
- adults aged 18-60 years
- individuals who had a mean systolic BP (SBP) between 130-160 mmHg and/or a diastolic BP (DBP) between 85-100 mmHg and no use of antihypertensive medications were identified as the proband
- the probands'parents, siblings, spouses, and offspring were recruited for the study.
Exclusion
- Secondary hypertension
- a history of severe cardiovascular disease
- chronic kidney disease or liver disease
- unable to complete the examination
- unable/refuse to sign the informed consent form
Key Trial Info
Start Date :
September 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
5611 Patients enrolled
Trial Details
Trial ID
NCT04471389
Start Date
September 1 2021
End Date
December 1 2022
Last Update
August 31 2021
Active Locations (1)
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1
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061