Status:
COMPLETED
Creatine Use and Muscle Stretching in Peripheral Artery Disease
Lead Sponsor:
Florida State University
Conditions:
Peripheral Arterial Disease
Eligibility:
All Genders
40-95 years
Phase:
PHASE2
Brief Summary
To utilize near-infrared spectroscopy to investigate if the research device, which induces muscle stretching, and creatine loading impact submaximal exercise performance in aged and PAD patients. Near...
Detailed Description
Lower extremity peripheral artery disease (PAD) has been estimated to impact nearly 8.5 million U.S. adults above the age of 40, significantly increasing the rate of morbidity and mortality with conco...
Eligibility Criteria
Inclusion
- Ankle-brachial index (ABI) of 0.90 or less in either leg or clinical diagnosis by a medical doctor (PAD group only)
- Stable condition for at least 3 months (PAD group only)
Exclusion
- Habitual exercise or cardiovascular rehabilitation program during the past 3 months
- Critical limb ischemia
- Blow or above-knee amputation
- Leg pain at rest
- Major surgery or lower extremity revascularization in the last 3 months
- Major medical illness treatment during the prior 12 months
- Central neurological disease
- Limited ankle or knee joint range of motion
- Requirement of oxygen with activity or exercise
- Heart failure
- Atrial fibrillation
- Wheelchair confinement or inability to walk
- Cognitive disorder
- Vasculitis problems including Takayasu's arteritis, Berger's disease, collagen disease or Reynaud's disease
- Overt cardiovascular disease
- Metabolic disease
- Renal disease
Key Trial Info
Start Date :
May 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2022
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT04471792
Start Date
May 12 2020
End Date
December 15 2022
Last Update
December 8 2025
Active Locations (1)
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1
Florida State University
Tallahassee, Florida, United States, 32304