Status:

COMPLETED

Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery

Lead Sponsor:

University of Minnesota

Conditions:

New Onset Atrial Fibrillation

Anesthesia, Local

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose if this pilot study is to determine if a perioperative infusion of 0.2% ropivacaine via bilateral T3 paravertebral catheters can decrease the incidence of new onset atrial fibrillation fol...

Detailed Description

Patients in the intervention group will have ultrasound guided bilateral T3 paravertebral catheters placed prior to surgery. Prior to surgery, these patients will have 5ml of 1.5% lidocaine with 1:200...

Eligibility Criteria

Inclusion

  • \- Participants must be undergoing one of the following elective or urgent (but not emergent) surgeries: A) Primary Coronary Artery Bypass Graft (CABG) B) Primary Surgical Aortic Valve Replacement (sAVR) C) Primary Surgical Mitral Valve Replacement (sMVR) D) Combined CABG \& surgical valve replacement

Exclusion

  • History of atrial fibrillation or flutter
  • Infective endocarditis
  • Left ventricular ejection fraction (LVEF) \< 30%
  • Emergency surgery
  • Redo surgery
  • Contraindication to block placement including local anesthetic allergy, bleeding diathesis (physiologic or iatrogenic)
  • Body mass index \> 35kg/m2
  • Pregnancy

Key Trial Info

Start Date :

April 9 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 8 2025

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT04472299

Start Date

April 9 2021

End Date

July 8 2025

Last Update

August 5 2025

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55455