Status:

TERMINATED

Cognitive Training in Stroke Rehabilitation

Lead Sponsor:

Weill Medical College of Cornell University

Conditions:

Executive Dysfunction

Cognitive Impairment

Eligibility:

All Genders

30-89 years

Phase:

NA

Brief Summary

This is a randomized, controlled pilot study to evaluate the efficacy of "ASCEND-I" (A Strategy and Computer-based intervention to ENhance Daily cognitive functioning after stroke - Inpatient), an inp...

Eligibility Criteria

Inclusion

  • Patient admitted for a stroke and accepted to acute inpatient rehabilitation at NYP-Weill Cornell.
  • Age 30-89
  • English speaking
  • Ability to comprehend sufficiently to participate in the treatment
  • Mild-moderate cognitive impairment as determined by a standard of care cognitive screening tools administered by occupational therapists (e.g., Montreal Cognitive Assessment, Symbol-Digit Modalities Test, or other clinical standard of care instrument). We will review subjects' most recent cognitive assessment administered by OT (Occupational Therapists) and available in the EMR (Electronic Medical Records) to determine eligibility.
  • Willingness to participate in full study duration
  • Physically able to operate a computer keyboard, tablet/iPad, and mouse.

Exclusion

  • History of other neurologic disorder (e.g., Parkinson's disease, Multiple Sclerosis, Alzheimer's disease, brain tumor). History of previous stroke(s) will not be exclusionary as long as the subject does not self-report having lasting/persistent cognitive impairment from the prior stroke.
  • History of severe mental illness (e.g., schizophrenia, psychosis) or substance use disorder, recent history (in the past year) of alcohol/substance use disorder or symptoms of psychosis. Note that the presence of post-stroke depression will not be grounds for exclusion.
  • History of dementia
  • Moderate-severe hemispatial neglect as determined by OT evaluation
  • Any factor that in the investigator's opinion is likely to compromise the subject's ability to participate in the study, including evidence that the subject may not understand and/or adhere to study requirements

Key Trial Info

Start Date :

January 12 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 15 2022

Estimated Enrollment :

27 Patients enrolled

Trial Details

Trial ID

NCT04472351

Start Date

January 12 2021

End Date

September 15 2022

Last Update

January 29 2025

Active Locations (1)

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Weill Cornell Medicine

New York, New York, United States, 10065