Status:
COMPLETED
Better Memory With Literacy Acquisition Later in Life
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
Federal University of Minas Gerais
National Institute on Aging (NIA)
Conditions:
Memory Impairment
Eligibility:
All Genders
40-89 years
Phase:
NA
Brief Summary
This study aims to discover whether acquiring basic-literacy in adulthood can improve episodic memory and brain structural and functional connectivity. In a collaborative project between Brazil and US...
Eligibility Criteria
Inclusion
- Being illiterate (TOFHLA score \<53) and availability to participate in the study for at least 12 months
Exclusion
- A) Presence of remarkable cognitive complains and/or decompensated psychiatric illness (depression and anxiety) and/or current substance abuse such as alcohol and illicit drugs use.
- B) Objective cognitive impairment: score of 2 standard deviations or bellow for age and education on the Mini-Mental State Evaluation (MMSE) and/or score of 6 or lower on the delayed recall task from the Brief Cognitive Battery.
- C) History of previously diagnosed dyslexia D) Formal MRI contraindications including metal or claustrophobia. E) Severe structural lesions detected by MRI.
Key Trial Info
Start Date :
November 11 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 17 2022
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT04473235
Start Date
November 11 2021
End Date
December 17 2022
Last Update
July 16 2024
Active Locations (1)
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1
Universidade Federal de Minas Gerais
Belo Horizonte, Minas Gerais, Brazil