Status:
COMPLETED
Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children
Lead Sponsor:
Institute of Tropical Medicine, Belgium
Collaborating Sponsors:
KU Leuven
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo
Conditions:
Bloodstream Infection
Salmonella Bacteremia
Eligibility:
All Genders
28-5 years
Brief Summary
In sub-Saharan Africa, non-typhoidal Salmonella (NTS) are a frequent cause of bloodstream infection, display high levels of antibiotic resistance and have a high case fatality rate (15%). In Kisantu h...
Eligibility Criteria
Inclusion
- Be a child of \> 28 days and \< 5 years old
- Be admitted to Kisantu Hospital
- Having a blood cultured sampled according to the criteria for suspected bloodstream infection embedded in the blood culture surveillance, i.e. presence of objective fever, hypothermia or history of fever during past 48 hours + at least one of the following criteria:
- Hypotension, confusion or increased respiratory rate
- Suspicion of severe localized infection: pneumonia, meningitis, osteomyelitis, complicated urinary tract infection, abscess, skin/soft tissue infection or abdominal infection
- Suspicion of typhoid fever
- Suspicion of severe Pf malaria
- Having a caregiver willing and able to provide written informed consent
Exclusion
- None
Key Trial Info
Start Date :
February 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 31 2022
Estimated Enrollment :
1880 Patients enrolled
Trial Details
Trial ID
NCT04473768
Start Date
February 1 2021
End Date
January 31 2022
Last Update
April 5 2022
Active Locations (1)
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1
Kisantu general referral hospital
Antwerp, Belgium, 2000