Status:
UNKNOWN
Weekly Use of Teriparatide to Accelerate Healing of Distal Radius Fracture
Lead Sponsor:
Peking University Third Hospital
Conditions:
Colles' Fracture
Eligibility:
FEMALE
45-75 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to examine the effect of weekly dosing strategy on fracture healing.
Eligibility Criteria
Inclusion
- Postmenopausal women aged 45-75 (at least 2 years after menopause)
- With primary osteoporosis
- Patients with Colles fractures with a fracture time of no more than 7 days
- conservative treatment after fracture (closed reduction and immobilization)
- no multiple fractures
- Informed well and agree to participate in this clinical trial
Exclusion
- Combine other physical diseases, including diabetes, severe hypertension, autoimmune diseases, heart, liver and kidney diseases, malignant tumors, mental illnesses, and other diseases that doctors believe may affect the healing process.
- In addition to primary osteoporosis, any disease affecting bone metabolism or treatment response, including serum PTH\>65pg/ml, 25-hydroxyvitamin D\<20ng/ml, alkaline phosphatase\>135U/L, history of bone tumor, Paget disease, history of radiotherapy
- The fracture site has a history of trauma or surgery, affecting the function of the wrist or forearm
- Those who are allergic to PTH or any excipients
- Currently receiving anti-osteoporosis treatment or receiving other anti-osteoporosis treatment during the trial
- Contraindication of teriparatide including hyperparathyroidism, severe renal insufficiency, hypercalcemia, etc.
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04473989
Start Date
June 1 2021
End Date
June 1 2024
Last Update
July 16 2020
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