Status:

UNKNOWN

Gene Mutation Spectrum of Malignant Hyperthermia in China

Lead Sponsor:

West China Hospital

Conditions:

Malignant Hyperthermia

Eligibility:

All Genders

Brief Summary

In this study, case information and specimens of patients with malignant hyperthermia(MH) will be collected from all over China, and gene fragment analysis, sanger sequencing method and/or high-throug...

Detailed Description

When MH cases or suspected cases occur in China, anesthesiologists can seek help through malignant hyperthermia emergency rescue WeChat group in which experts from all over the country will give thera...

Eligibility Criteria

Inclusion

  • Chinese whose malignant hyperthermia susceptibility had been confirmed after a positive clinical manifestation of malignant hyperthermia which defined as their scores of clinical grading scale for malignant hyperthermia are more than 35 and their blood relations.
  • Sign informed consent

Exclusion

  • Patients who have no adverse anaesthetic event, such as those patients referred with a history of exertional heat illness, exertional or recurrent rhabdomyolysis, or a congenital myopathy.

Key Trial Info

Start Date :

January 15 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04474860

Start Date

January 15 2019

End Date

January 1 2024

Last Update

November 10 2021

Active Locations (1)

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West China Hospital, Sichuan University

Chengdu, Sichuan, China, 610041

Gene Mutation Spectrum of Malignant Hyperthermia in China | DecenTrialz