Status:

UNKNOWN

Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies

Lead Sponsor:

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Conditions:

Breast Cancer

Gynecologic Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The main purpose of this study is to evaluate the impact of food supplements (herbal remedies) on sign and symptoms induced by cancer therapies: Nettle will be administered for improvement of anemia a...

Eligibility Criteria

Inclusion

  • Male or Female ≥ 18 years
  • Karnofsky Performance Scale (KPS) ≥ 90%
  • Breast or Gynecological cancer
  • Informed consent signed before every procedure study specific, on day 1 of therapy cycle
  • Inclusion Criteria Arm 1: presence of grade 1 anemia as per CTCAE 4.0 criteria; patients on treatment with anti-CDK 4/6 or PARP Inhibitors or in adjuvant therapy with hormone therapy
  • Inclusion Criteria Arm 2: presence of fatigue of any grade; patients on treatment with Epirubicin and Cyclophosphamide or Carboplatin and Taxane
  • Inclusion Criteria Arm 3: presence of nausea of any grade, without vomiting; patients on treatment with Epirubicin and Cyclophosphamide or Carboplatin and Taxane

Exclusion

  • Arm 1, 2 and 3: Previous intake of food supplements within 4 weeks from the enrollment
  • Arm 2: patients with evidence of anxiety or anxious-depressive syndrome; Clinical hypothyroidism not compensated by replacement therapy; Persistent insomnia
  • Arm 3: patients with evidence of anxiety or anxious-depressive syndrome

Key Trial Info

Start Date :

June 20 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04474951

Start Date

June 20 2019

End Date

September 1 2021

Last Update

July 17 2020

Active Locations (1)

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1

Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, SSD Oncologia Medica Addarii

Bologna, Italy, 40138