Status:
UNKNOWN
ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial Infarction
Lead Sponsor:
Collegium Medicum w Bydgoszczy
Conditions:
ST Elevation Myocardial Infarction
Non ST Segment Elevation Acute Coronary Syndrome
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to evaluate analgesic efficacy of inhaled methoxyflurane vs intravenous morphine in patients presenting with acute ST-elevation (STEMI) / non ST-elevation acute coronary s...
Detailed Description
Platelet activation plays a pivotal role in the pathophysiology of acute coronary syndromes (ACS). Pharmacological platelet inhibition with P2Y12 receptor antagonists and aspirin, together with percut...
Eligibility Criteria
Inclusion
- diagnosis of ST-elevation myocardial infarction (STEMI) or non-ST-elevation acute coronary syndrome (NSTE-ACS)
- patients aged from 18 to 80 years
Exclusion
- pregnancy
- manifest infection or inflammatory state
- cardiogenic shock during screening for eligibility
- respiratory failure
- heart failure (NYHA class III or IV during screening for eligibility)
- uncontrolled hypertension (systolic blood pressure \>180 mmHg or diastolic blood pressure \>100 mmHg)
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04476173
Start Date
June 1 2020
End Date
December 30 2024
Last Update
September 11 2023
Active Locations (1)
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1
Department of Cardiology
Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland, 85-094