Status:
COMPLETED
Prognostication of Recovery in Early Disorders of Consciousness After COVID-19
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Covid19
Coma
Eligibility:
All Genders
18+ years
Brief Summary
The primary aim of this research proposal is to use multimodal metrics (e.g., clinical data and advanced neuroimaging) in the early (i.e., acute hospitalization) phase of recovery from COVID-19-relate...
Eligibility Criteria
Inclusion
- age 18 or older,
- positive diagnosis of COVID-19,
- diagnosis of coma, vegetative state or minimally conscious state per Glasgow Coma Scale (GCS) at time of enrollment (excluding confounders such as sedation) and
- clinical team plan for an MRI for clinical management.
Exclusion
- A subject with any of the following MRI contraindications will not be eligible for this study:
- electrical implants such as cardiac pacemakers or perfusion pumps
- ferromagnetic implants such as aneurysm clips, surgical clips, prostheses, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants
- ferromagnetic objects such as jewelry or metal clips in clothing that cannnot be easily removed for scanning
- pregnant volunteers
Key Trial Info
Start Date :
July 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 7 2022
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT04476589
Start Date
July 1 2020
End Date
April 7 2022
Last Update
April 4 2023
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114