Status:

RECRUITING

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

Lead Sponsor:

Boston Children's Hospital

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Brief Resolved Unexplained Event

Apparent Life Threatening Event

Eligibility:

All Genders

Up to 12 years

Brief Summary

This observational study will examine the effects of thickened feeds on clinical outcomes and healthcare utilization in infants with brief resolved unexplained event (BRUE).

Detailed Description

Brief resolved unexplained events (BRUE) are frightening episodes characterized by the appearance of life-threatening choking, pallor, cyanosis, and limpness in infants. These common events are resour...

Eligibility Criteria

Inclusion

  • Less than 1 year of age
  • Admitted to Boston Children's Hospital after experiencing first lifetime brief resolved unexplained event.

Exclusion

  • Any pre-existing medical diagnoses that exclude brief resolved unexplained event diagnosis including seizure disorders and cyanotic congenital heart disease
  • Already receiving thickened liquids for treatment of another condition

Key Trial Info

Start Date :

April 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 31 2026

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT04477460

Start Date

April 1 2021

End Date

August 31 2026

Last Update

December 10 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115