Status:

COMPLETED

Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery

Lead Sponsor:

China Medical University, China

Conditions:

Sleep Deprivation

Eligibility:

MALE

18-75 years

Phase:

PHASE4

Brief Summary

It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing video ...

Detailed Description

This study is a prospective, randomized, controlled (randomized, parallel group, concealed allocation), double-blinded trial. All patients undergoing video assisted thoracic surgery during morning wil...

Eligibility Criteria

Inclusion

  • • 1. ethnic Chinese;
  • • 2. age, 18 to 75 years old;
  • • 3. American Society of Anaesthesiologists (ASA) physical status I or II;
  • • 4. required VATS for lung surgery and one lung ventilation

Exclusion

  • Cognitive difficulties
  • • Partial or complete gastrectomy
  • • Previous esophageal surgery
  • • Previous treated by radiotherapy or surgery
  • • Inability to conform to the study's requirements
  • • body mass index exceeding 30 kg/m2
  • • Deprivation of a right to decide by an administrative or juridical entity
  • • Ongoing participation or participation in another study \<1 month ago
  • • preoperative Pittsburgh Sleep Quality Index global scores higher than 6
  • • recent (\< 3 months prior) use of antibiotics, probiotics, prebiotics, symbiotics, hormonal medication, laxatives, proton pump inhibitors, insulin sensitizers or traditional Chinese medicine

Key Trial Info

Start Date :

November 6 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2022

Estimated Enrollment :

51 Patients enrolled

Trial Details

Trial ID

NCT04479566

Start Date

November 6 2020

End Date

January 31 2022

Last Update

February 4 2022

Active Locations (1)

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1

the First Hospital of China Medical University

Shenyang, Liaoning, China, 110001