Status:
COMPLETED
Transthoracic Echocardiography of Ventricular Function of Parturients in Labor
Lead Sponsor:
Dartmouth-Hitchcock Medical Center
Conditions:
Obstetric Labor Complications
Cardiovascular Diseases in Pregnancy
Eligibility:
FEMALE
18-35 years
Brief Summary
This echocardiography study will characterize heart structure and function during labor. Imaging of the heart during the stress of labor could increase detection of subclinical cardiovascular disease ...
Eligibility Criteria
Inclusion
- All healthy parturients 18 years of age or older with estimated gestation greater than or equal to 37 weeks who are expected to deliver during their hospitalization.
- During the echocardiographic exam, the patient must be in active labor with cervical dilation between 6-10 cm and contractions that are spaced less than 5 minutes apart.
Exclusion
- Known functional or structural heart disease
- Previously diagnosed pulmonary hypertension.
- Comorbid disease other than diet controlled gestational diabetes, uncomplicated obesity, mild asthma and euthyroid patients with a history of hypo or hyperthyroidism.
- Parturients endorsing active use of non-prescription mind-altering drugs including cocaine, methamphetamine, or ketamine.
- Other non-inclusion criteria include inability to tolerate left lateral positioning either symptomatically or by fetal heart rate monitoring, suspected hypo-or hypercoagulable states that was not previously diagnosed, hemodynamic instability requiring \>2 L crystalloid administration within 1 hour time frame after epidural placement or vasopressor administration of \>15 mg ephedrine or \>300 mcg phenylephrine administration within 1 hour after epidural placement.
Key Trial Info
Start Date :
September 5 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04481503
Start Date
September 5 2020
End Date
May 1 2024
Last Update
November 15 2024
Active Locations (1)
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1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03766