Status:

COMPLETED

Low-Level Laser in Head and Neck Chronic Lymphedema

Lead Sponsor:

Abramson Cancer Center at Penn Medicine

Conditions:

Head and Neck Cancer

Lymphedema

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effect of low-level laser treatment (LLLT) on the severity of lymphedema, symptom burden, functional status, and quality of life in HNC survivors.

Detailed Description

Primary aim: To determine the impact of LLLT, as compared to wait-list control, on changes in severity of lymphedema. Secondary aim: To determine the impact of LLLT, as compared to a wait-list contro...

Eligibility Criteria

Inclusion

  • \>18 years of age
  • \>6 months post HNC treatment
  • No evidence of cancer confirmed with imaging tests
  • Having head and neck lymphedema with or without fibrosis
  • Completion of initial lymphedema therapy
  • Lymphedema duration between 3-24 months
  • Ability to speak and read English
  • Ability to provide informed consent

Exclusion

  • Patients will be excluded if they have any of the following medical conditions that would prohibit the safe implementation of LLLT:
  • Pregnancy
  • Acute infection
  • Photosensitivity
  • Chronic inflammatory diseases
  • Venous thrombosis
  • Carotid artery stenosis
  • History of severe trauma
  • Medication that affects body fluid and electrolyte balance
  • Use of high doses of non-steroidal anti-inflammatory drugs
  • Pre-existing skin rash, ulceration, open wound in the treatment area
  • Active lymphedema therapy or physical therapy
  • Allergic and other systemic skin diseases

Key Trial Info

Start Date :

August 19 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2023

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT04482855

Start Date

August 19 2021

End Date

June 30 2023

Last Update

November 19 2024

Active Locations (1)

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1

University of Pennsylvania Abramson Cancer Center

Philadelphia, Pennsylvania, United States, 19104