Status:

COMPLETED

Intraoperative Carbetocin to Decrease Blood Loss During Hysteroscopic Myomectomy

Lead Sponsor:

Mansoura University Hospital

Conditions:

Myoma;Uterus

Eligibility:

FEMALE

18-45 years

Phase:

PHASE4

Brief Summary

Submucous myomas represent one of the main indications of operative hysteroscopy. Since 1976 when Neuwirth and Amin reported the first five cases of excision of submucous myomas , several techniques h...

Detailed Description

All patients will have preoperative evaluation by gynecologists and anesthetists, with history taking and pelvic examination. A TVS scan will be done to determine the number, size and location of the ...

Eligibility Criteria

Inclusion

  • Symptomatic women aged 18-45 years diagnosed by transvaginal sonography (TVS) to have single type 0 or I submucous uterine myomas according to FIGO classification system with a largest diameter ≤ 4 cm and myometrial free margin of at least 10 mm.

Exclusion

  • • Age \< 18 or \> 45 years.
  • Uterine septum or structural uterine abnormality (including multiple uterine fibroids and/or multiple submucous myomas)
  • Present or history of cervical or uterine malignancies.
  • Active pelvic infection.
  • Chronic medical diseases (cardiopulmonary, thromboembolic, hepatic, or renal diseases).
  • Bleeding disorders.
  • Patients receiving anticoagulant therapy.
  • Patients receiving gonadotropin-releasing hormone (GnRH) analogues.
  • History of adverse reaction contraindications for Carbetocin.

Key Trial Info

Start Date :

July 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2022

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04482959

Start Date

July 15 2020

End Date

February 1 2022

Last Update

April 6 2022

Active Locations (1)

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1

Faculty of Medicine

Al Mansurah, Dakahlia Governorate, Egypt, 050