Status:

COMPLETED

Place of Circulating Biomarkers and Respiratory Eicosanoids in the Prognosis of Severe Forms of Covid-19 Pneumonia

Lead Sponsor:

Fondation Hôpital Saint-Joseph

Collaborating Sponsors:

Versailles Hospital

Centre Hospitalier Victor Dupouy

Conditions:

Coronavirus

Covid19

Eligibility:

All Genders

18+ years

Brief Summary

The research is a prospective, multicentric (Groupe hospitalier Paris Saint-Joseph, Centre Hospitalier de Versailles André Mignot and Centre Hospitalier Victor Dupouy), non-interventional, prospective...

Detailed Description

The reason for the involvement of overweight in the severity of viral respiratory pathologies, particularly during influenza and coronavirus infections, has been the subject of numerous studies which ...

Eligibility Criteria

Inclusion

  • Patient aged over 18 years
  • French-speaking
  • Patient whose Covid-19 respiratory infection was confirmed by laboratory tests, PCR and any other commercial or public health tests
  • Patient hospitalized in intensive care unit and under invasive mechanical ventilation for less than three days (early inflammatory phase)
  • Adult acute respiratory distress syndrome according to the Berlin definition
  • Patient on long-term statin therapy regardless of the rationale for treatment (or without treatment for the control group).

Exclusion

  • Patient/family or "medical" proxy who refuses the patient's participation in the study
  • Patient under guardianship or curatorship
  • Patient deprived of liberty
  • Patient under the safeguard of justice.

Key Trial Info

Start Date :

April 14 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 6 2022

Estimated Enrollment :

97 Patients enrolled

Trial Details

Trial ID

NCT04485364

Start Date

April 14 2020

End Date

June 6 2022

Last Update

March 7 2023

Active Locations (1)

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Groupe Hospitalier Paris Saint-Joseph

Paris, France, 75014