Status:
COMPLETED
RESIST-ADT (Androgen Deprivation Therapy)
Lead Sponsor:
Dana-Farber Cancer Institute
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Prostate Cancer
Physical Function
Eligibility:
MALE
60+ years
Phase:
NA
Brief Summary
The overall goal of this study is to determine if implementing structured exercises prevent decline in muscle mass, muscle strength and physical function in men with prostate cancer undergoing androge...
Detailed Description
This randomized, controlled, parallel group trial of 6-months duration is determining the efficacy of structured resistance exercise training in preventing the decline in physical function in older me...
Eligibility Criteria
Inclusion
- Men with active Prostate Cancer who are 60 years or older.
- Hormone-naive men about to undergo medical or surgical ADT.
- Planned ADT for at least 6 months.
- Life expectancy of at least 6 months from enrollment.
- Ability and willingness to provide informed consent.
Exclusion
- Active medical conditions affecting participation in exercise training (limiting arthropathies, myopathies, severe peripheral vascular disease, or severe neuropathy).
- Cardiovascular disease (current angina, severe valvular disease, advanced congestive heart failure, arrhythmias, or stroke with residual muscular weakness).
- Prior hip or knee replacement.
- History of lower extremity fracture in the past 6 months.
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT04485767
Start Date
December 1 2020
End Date
September 30 2023
Last Update
August 20 2024
Active Locations (2)
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1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02066
2
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115