Status:
RECRUITING
Lateral Nodal Recurrence in Rectal Cancer
Lead Sponsor:
Amsterdam UMC, location VUmc
Conditions:
Rectal Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Local recurrence rates in rectal cancer have reduced dramatically since the introduction of the total mesorectal excision (TME) technique and neoadjuvant (chemo)radiotherapy (C))RT) to overall rates o...
Detailed Description
Local recurrence rates in rectal cancer have reduced dramatically since the introduction of the total mesorectal excision (TME) technique. These rates have been lowered further with the use of neoadju...
Eligibility Criteria
Inclusion
- • All patients with rectal cancer with one or more lateral nodes with a short-axis of ≥7mm or ≥5mm with one or more malignant features (i.e. round shape, irregular margins, heterogeneity, loss of fatty hilum).
Exclusion
- Younger than 18 years old
- Pelvic irradiation in the medical history
- Previous lateral lymph node dissection related to pelvic malignancy
- Synchronous distant metastases
- Familiar adenomatous polyposis
- Synchronous colon cancer with a higher stage than rectal cancer
- Absolute contraindication for general anaesthesia
- Pregnancy
Key Trial Info
Start Date :
October 6 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04486131
Start Date
October 6 2020
End Date
October 1 2026
Last Update
January 19 2023
Active Locations (1)
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1
Amsterdam University Medical Centers
Amsterdam, North Holland, Netherlands, 1081 HV