Status:

COMPLETED

High-intensity Strength Training in Myositis

Lead Sponsor:

Rigshospitalet, Denmark

Collaborating Sponsors:

University of Southern Denmark

Odense University Hospital

Conditions:

Myositis

Dermatomyositis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study evaluates the effects of a high-intensity strength training in patients with myositis with the primary outcome being quality of life (SF-36). The study is designed as a parallel group rando...

Detailed Description

Overall aim: To investigate the effect of high-intensity strength training on quality of life, muscle strength, physical function, and disease activity in patients with myositis Study design: 60 my...

Eligibility Criteria

Inclusion

  • Fulfilling the criteria for myositis by EULAR/ACR (Bottai et al., 2017; Lundberg et al., 2017)
  • ≤ 5 mg/day Prednisolone
  • Stable dosage of immunosuppressive treatment for at least 1 months prior to inclusion in the study
  • Myositis diagnosis at least 6 months prior to inclusion in the study

Exclusion

  • Patients with sporadic inclusion body myositis and overlap myositis (myositis combined with another autoimmune rheumatic diseases, except Sjögren's Syndrome)
  • Co-morbidity preventing resistance training (severe heart/lung-disease, uncontrolled hypertension (systolic \> 160mmHg, diastolic \> 100mmHg), severe knee/hip arthritis)
  • Alcohol- and/or drug abuse. Defined by the guidelines issued by The Danish Health Authority

Key Trial Info

Start Date :

August 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2023

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT04486261

Start Date

August 30 2021

End Date

January 1 2023

Last Update

April 10 2024

Active Locations (1)

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1

Rigshospitalet

Copenhagen, Denmark, 2100