Status:

UNKNOWN

Macroscopic on Site Evaluation (MOLSE) vs Standard Specimen Acquisition of Solid Lesions During EUS-FNB

Lead Sponsor:

Istituto Clinico Humanitas

Collaborating Sponsors:

Istituto Clinico Humanitas Mater Domini

Conditions:

Endoscopic Ultrasonography With Tissue Acquisition

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Endoscopic ultrasonography (EUS) with tissue acquisition (TA) is nowadays a well-established technique for the sampling of solid lesions pancreatic and non-pancreatic lesions. Actually the standard me...

Eligibility Criteria

Inclusion

  • Age greater than 18, both genders.
  • Both in-patient and out-patients.
  • Presence of a solid lesion. In the presence of a cystic component, the solid part of the lesion should be more 75% of the total.
  • FNB performed by a 22G needle Acquire® (Boston Scientific).
  • Tissue acquisition with fanning technique.
  • Obtained informed consent.

Exclusion

  • Patients underwent EUS-FNA with or without ROSE
  • Patients underwent EUS-FNB plus ROSE.
  • Previous biopsy of the lesion with diagnosis of malignancy
  • Presence of an uncorrectable coagulopathy as defined by abnormal prothrombin time (PT) or partial thromboplastin time (PTT) that does not normalize after administration of fresh frozen plasma.
  • Pregnancy or breast-feeding.
  • Patients unable to understand and/or read the consent form.
  • Inclusion in other study.

Key Trial Info

Start Date :

July 17 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2021

Estimated Enrollment :

370 Patients enrolled

Trial Details

Trial ID

NCT04486274

Start Date

July 17 2020

End Date

July 31 2021

Last Update

July 24 2020

Active Locations (1)

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1

Gastrointestinal Endoscopy Unit

Castellanza, Italy