Status:
UNKNOWN
Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2
Lead Sponsor:
Sanatorio Anchorena San Martin
Conditions:
Covid19
ARDS, Human
Eligibility:
All Genders
18+ years
Brief Summary
The combination of different ventilatory strategies and its effects on respiratory mechanics and gas exchange in patients under mechanical ventilation with acute respiratory distress syndrome secondar...
Detailed Description
Investigation in mechanically ventilated patients with with acute respiratory distress syndrome (ARDS) secondary to coronavirus-19 (COVID-19) is emerging due to presumed differences with typical ARDS ...
Eligibility Criteria
Inclusion
- Older than 18 years old
- less than 72 hs since ARDS diagnosis
- Moderate to severe ARDS
- central venous catheter and arterial line available
- Need of neuromuscular blocking agents
- Supine position
- Informed consent accepted
- Airway opening pressure lower than 20 cmH2O
Exclusion
- RASS target higher than -5
- COPD diagnosis
- Pneumothorax
- Intracraneal Hypertension
- Pregnancy
- Cardiac inssuficiency uncompensated
- Chest wall deformity
- Bronchopleural fistula
- Contraindication to use esophageal manometry
Key Trial Info
Start Date :
July 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 20 2020
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04486729
Start Date
July 1 2020
End Date
October 20 2020
Last Update
July 27 2020
Active Locations (1)
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1
Sanatorio Anchorena San Martin
San Martín, Buenos Aires, Argentina