Status:
UNKNOWN
Characterization of Novel Lipoprotein Properties Associated With an Increased Risk to Develop Atherosclerosis
Lead Sponsor:
Sheba Medical Center
Conditions:
Atherosclerosis
Eligibility:
All Genders
18+ years
Brief Summary
Objectives of Medical Research: Separation of LDL and HDL from blood samples of patients with high LDL and / or low HDL who have developed atherosclerotic disease with similar patients who have no ev...
Detailed Description
Participants: Participants who are found suitable during their visit to the Lipid Institute Clinic or during hospitalization at the Sheba Medical Center will receive an explanation of the study, will...
Eligibility Criteria
Inclusion
- Healthy participants with LDL levels less than 130 mg / dl without evidence of atherosclerosis or wall thickening of the carotid artery according to an ultrasound imaging of the carotid artery at the Lipid Institute and unknown for atherosclerosis or cardiovascular disease in the background.
- Participants with LDL levels above 160 mg / dl, with no evidence of atherosclerosis or wall thickening of the carotid artery according to an ultrasound - IMT of the carotid arteries performed at the Lipid Institute and unknown for atherosclerosis or cardiovascular disease in the background.
- Participants with LDL levels above 160 mg / dl, where evidence of atherosclerosis or wall thickening of the arteries can be found by ultrasound imaging of the carotid artery that is performed at the Lipid Institute or known for atherosclerosis or cardiovascular disease in the background.
Exclusion
- Patients with triglyceride values above 300 mg%, HDL lower than 30 mg%, APOB greater than 150 mg% or LPa higher than 70 mg% will not be included in the study
Key Trial Info
Start Date :
April 27 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 27 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04487223
Start Date
April 27 2020
End Date
April 27 2022
Last Update
October 4 2021
Active Locations (1)
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1
Lipid center
Tel Litwinsky, Israel, 5265601