Status:
UNKNOWN
Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain
Lead Sponsor:
Boston Children's Hospital
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Chronic Widespread Pain
Stress, Psychological
Eligibility:
All Genders
11-17 years
Phase:
NA
Brief Summary
Chronic widespread pain (CWP) is a common chronic pain condition in youth and often associated with significant pain-related and psychosocial impairment. Understanding the neurobiological mechanisms t...
Detailed Description
Pediatric chronic widespread pain (CWP) is a serious public health problem resulting in high levels of healthcare utilization and disability. Youth with CWP also frequently report exposure to adverse ...
Eligibility Criteria
Inclusion
- Chronic Widespread Pain (CWP) group:
- Between ages 11-17 years
- Referred to the Boston Children's Hospital Pain Treatment Service for evaluation of a CWP condition with duration \> 3 months
- Right-handed
Exclusion
- Inability to speak sufficient English to complete questionnaires
- Severe cognitive impairment
- Prescription steroidal (interference with cortisol measures) or psychotropic medication
- Any other chronic pain diagnosis (e.g., migraines, abdominal pain, CRPS)
- fMRI contraindications (e.g., dental appliances)
- Healthy Control (HC) group:
- Inclusion Criteria:
- Between ages 11-17 years
- Right-handed
Key Trial Info
Start Date :
November 4 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2024
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04488757
Start Date
November 4 2021
End Date
August 31 2024
Last Update
October 19 2023
Active Locations (1)
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1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115