Status:
COMPLETED
Effects of Aerobic Training on Pancreatic Fat and Cognitive Function in T2DM Patients
Lead Sponsor:
Nanjing University of Traditional Chinese Medicine
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
60-75 years
Phase:
NA
Brief Summary
The primary aim of this study was to evaluate the difference in cognitive function and brain functional structure between exercise group and control group by performing regular one-year moderate-inten...
Detailed Description
In recent years, more attention has been paid to the role of aerobic exercise in improving cognitive ability, but there is still a lack of prospective studies on the T2DM population with normal cognit...
Eligibility Criteria
Inclusion
- Diagnosed of T2DM based on the 1999 diagnostic criteria of the WHO;
- Had normal muscle strength; 3.18.5≤BMI≤35kg/m2;
- Had normal cognitive function ( MMSE ≥27 points, MoCA ≥26 points) ; 5.Primary school education or above ( Participants were able to fill in the scale) ; 6.Aged 60-75 years; 7.Had ≥5 years duration of T2DM; 8.Had no evidence of hearing or visual impairment and communication difficulties; 9.Were willing to participate in the study and signed informed consent voluntarily.
Exclusion
- With severe acute complications of diabetes;
- Serious heart, liver and kidney dysfunction, and cardiovascular and cerebrovascular diseases, such as cerebral infarction, cerebral hemorrhage, etc.;
- Pregnant and lactating women;
- Sleep disorders (PSQI \>7 points);
- Had a family history of dementia;
- Alcohol dependence and oral medications that affect cognitive function (such as antipsychotic drugs, sedative hypnotics, etc.);
- Contraindications for MRI, such as metal implant in the body.
Key Trial Info
Start Date :
December 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2020
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT04489966
Start Date
December 1 2018
End Date
March 20 2020
Last Update
January 5 2021
Active Locations (1)
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1
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
Nanjing, Jiangsu, China, 210028