Status:

COMPLETED

Serological Surveillance for COVID-19 in Central North Carolina

Lead Sponsor:

National Institute of Environmental Health Sciences (NIEHS)

Conditions:

COVID-19

Eligibility:

All Genders

18-100 years

Brief Summary

Background: The SARS-CoV-2 virus has caused a pandemic. Little is known about the virus, so data is needed to form an effective public health response. Researchers want to count how many people have ...

Detailed Description

It has been demonstrated that respiratory virus outbreaks and pandemics, such as influenza, SARS, MERS, and now the newly emerged SARS-CoV-2 virus, have a major impact on morbidity and mortality world...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • Male and females
  • greater than or equal to 18 years of age
  • Able to read and speak English
  • Ability to provide informed consent
  • Able to travel to study visits at the NIEHS CRU for required study visits
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • EXCLUSION CRITERIA:
  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • Current symptoms consistent with COVID-19 infection at the point of Antibody Visit 1
  • Inability to provide a blood sample
  • Current pregnancy or lactation, by participant verbal confirmation.
  • Any condition that, in the investigator's opinion, places the participant at undue risk for complications associated with required study procedures.
  • Not willing to have blood samples stored for future research
  • Participants who have Limited English Proficiency will be excluded from the study because the informed consent form is only available in English. The study documents (Demographic and Health Assessment Questionnaire, and Weekly Symptom Questionnaire) and FDA Fact Sheets for Tests with Emergency Use Authorization are only available in English.
  • Decisionally impaired adults and prisoners will be excluded due to the inability to complete necessary study procedures. Adults who become prisoners or decisionally impaired while on study will be withdrawn.
  • Pregnant women are excluded due to the need to have participants venture out during the COVID-19 pandemic. Women who become pregnant during the study will be withdrawn.
  • Children will be excluded from enrolling in this study as immunity in children is different than
  • adults and we are focusing on adult immunity and in this trial

Exclusion

    Key Trial Info

    Start Date :

    August 24 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 5 2023

    Estimated Enrollment :

    643 Patients enrolled

    Trial Details

    Trial ID

    NCT04490174

    Start Date

    August 24 2020

    End Date

    December 5 2023

    Last Update

    September 12 2025

    Active Locations (1)

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    1

    NIEHS Clinical Research Unit (CRU)

    Research Triangle Park, North Carolina, United States, 27709